IBB is a Sector & Thematic ETF from iShares holding 254 positions as of Mar 31, 2026, with $9.3B in assets and a 0.44% net expense ratio. Its largest positions are GILD (7.7%), AMGN (7.5%) and VRTX (7.4%); the top 10 holdings account for 47.4% of the portfolio. It yields 0.21% on a trailing-12-month basis.
- Issuer
- iShares
- Holdings
- 2549.8% cash, collateral & derivative positions excluded
- Net Assets
- $9.3BETF assets as of 2026-08-10
- Expense Ratio
- 0.44%per latest SEC prospectus filing
- TTM Yield
- 0.21%trailing 12-month distributions
Performance
- 1M
- -0.3%
- YTD
- +17.3%
- 1Y
- +51.0%
- 3Y (ann.)
- +16.4%
- 5Y (ann.)
- +3.1%
- 10Y (ann.)
- +7.4%
A $10,000 investment 10 years ago would be worth $20,477 today at the 10Y annualized rate. This is a backward-looking illustration, not a forecast. Project its future growth →
Total returns including dividends as of 2026-08-07. 3Y/5Y/10Y annualized. Past performance does not predict future results.
Sector Breakdown
| Health Care | 91.0% |
|---|---|
| Other Sectors | 0.0% |
| Unclassified | 8.9% |
We could not classify 9% of portfolio weight. It is shown separately as “Unclassified”, not lumped into a sector.
Top 25 Holdings
| # | Holding | Weight |
|---|---|---|
| 1 |  GILDGilead Sciences, Inc. | 7.75% |
| 2 |  AMGNAmgen, Inc. | 7.51% |
| 3 |  VRTXVertex Pharmaceuticals, Inc. | 7.44% |
| 4 |  REGNRegeneron Pharmaceuticals, Inc. | 7.21% |
| 5 |  ALNYAlnylam Pharmaceuticals, Inc. | 3.99% |
| 6 |  INSMInsmed, Inc. | 3.20% |
| 7 |  ARGXArgenx SE | 3.07% |
| 8 |  BIIBBiogen, Inc. | 2.46% |
| 9 |  NTRANatera, Inc. | 2.41% |
| 10 |  UTHRUnited Therapeutics Corp. | 2.30% |
| 11 |  ONCBeOne Medicines Ltd. | 1.93% |
| 12 |  INCYIncyte Corp. | 1.70% |
| 13 |  MRNAModerna, Inc. | 1.68% |
| 14 |  ILMNIllumina, Inc. | 1.68% |
| 15 |  RVMDRevolution Medicines, Inc. | 1.54% |
| 16 |  ROIVRoivant Sciences Ltd. | 1.24% |
| 17 |  NBIXNeurocrine Biosciences, Inc. | 1.18% |
| 18 |  GMABGenmab A/S | 1.17% |
| 19 |  BBIOBridgebio Pharma, Inc. | 1.13% |
| 20 |  IONSIonis Pharmaceuticals, Inc. | 1.11% |
| 21 |  MEDPMedpace Holdings, Inc. | 1.00% |
| 22 |  MDGLMadrigal Pharmaceuticals, Inc. | 1.00% |
| 23 |  EXELExelixis, Inc. | 0.99% |
| 24 |  BMRNBioMarin Pharmaceutical, Inc. | 0.98% |
| 25 | Ascendis Pharma A/S | 0.96% |
Showing the top 25 of 254 holdings. See the full IBB holdings list →
IBB alternatives
The closest Sector & Thematic ETFs to IBB by portfolio overlap — the share of weight both funds hold in the same securities.
| Fund | Overlap | Expense | Assets | |
|---|---|---|---|---|
 XBIState Street® SPDR® S&P® Biotech ETF | 39% | 0.35%cheaper | $10.0B | Compare → |
| 18% | 0.08%cheaper | $3.3B | Compare → | |
 VHTVanguard Health Care Index Fund | 18% | 0.09%cheaper | $18.3B | Compare → |
 IYHiShares U.S. Healthcare ETF | 16% | 0.38%cheaper | $3.7B | Compare → |
 RSPHInvesco S&P 500 Equal Weight Health Care ETF | 13% | 0.4%cheaper | $776M | Compare → |
 XLVState Street® Health Care Select Sector SPDR® ETF | 11% | 0.08%cheaper | $41.9B | Compare → |
 ARKGARK Genomic Revolution ETF | 9% | 0.75%pricier | $1.6B | Compare → |
 ARKKARK Innovation ETF | 4% | 0.75%pricier | $6.0B | Compare → |
Frequently Asked Questions
What is IBB's expense ratio?
IBB has a net expense ratio of 0.44%, per its latest SEC prospectus filing. That works out to about $44 a year on a $10,000 investment.
How many holdings does IBB have?
IBB held 254 positions as of Mar 31, 2026, per its latest official holdings data. Cash, collateral and derivative positions (9.8% of portfolio weight) are excluded from that count.
What are IBB's top 10 holdings?
IBB's largest positions are GILD (7.7%), AMGN (7.5%), VRTX (7.4%), REGN (7.2%), ALNY (4.0%), INSM (3.2%), ARGX (3.1%), BIIB (2.5%), NTRA (2.4%), UTHR (2.3%). Together they account for 47.4% of the portfolio.
What is IBB's dividend yield?
IBB yields 0.21% based on its trailing 12-month distributions, as of Aug 7, 2026.
How big is IBB?
IBB has $9.3B in assets as of Aug 10, 2026.
What are good alternatives to IBB?
By portfolio overlap, the closest Sector & Thematic ETFs to IBB are XBI (39% overlap), FHLC (18% overlap), VHT (18% overlap). Overlap measures the share of portfolio weight both funds hold in the same securities.