IYH vs XBI: Holdings Overlap
IYHiShares U.S. Healthcare ETF
iShares · 103 holdings · $3.7B · as of 2026-04-30
XBIState Street® SPDR® S&P® Biotech ETF
State Street (SPDR) · 149 holdings · $10.0B · as of 2026-08-06
Holdings snapshots are 98 days apart (IYH: 2026-04-30, XBI: 2026-08-06). Weights and index membership change between snapshots, so the true current overlap is typically higher than shown. For funds tracking the same index, the gap can be 5–15 points.
How similar are IYH and XBI?
iShares U.S. Healthcare ETF (IYH, by iShares) holds 103 positions; State Street® SPDR® S&P® Biotech ETF (XBI, by State Street (SPDR)) holds 149. They have 23 holdings in common, and by portfolio weight the two funds are 10.7% identical. In practical terms the pair is lightly overlapping, with most of each portfolio distinct.
- Overlap by Weight
- 10.7%Sum of the smaller weight of each shared holding
- Shared Holdings
- 23IYH holds 103 · XBI holds 149
- Weight in Shared Holdings
- IYH 22%·XBI 24%Share of each fund's weight in stocks both funds own
Based on each fund's latest official holdings. How is this calculated?
What makes each fund different
Only in IYH
80 of 103 positions (78.1% of the fund) are not held by XBI. Showing the top 30 by weight.
Only in XBI
126 of 149 positions (75.8% of the fund) are not held by IYH. Showing the top 30 by weight.
Sector Breakdown
| Sector | IYH | XBI |
|---|---|---|
| Health Care | 99.8% | 95.5% |
| Other Sectors | 0.0% | 0.0% |
| Unclassified | 0.0% | 4.6% |
Share of each fund's portfolio weight by GICS-style sector, compiled from issuer fund data and our own classification of the holdings, not the issuers' published sector charts. “Unclassified” is weight we could not classify (0% of IYH, 5% of XBI).
Performance
| Fund | 1M | YTD | 1Y | 3Y (ann.) | 5Y (ann.) | 10Y (ann.) | Yield |
|---|---|---|---|---|---|---|---|
| IYH | +0.6% | +8.1% | +30.4% | +8.9% | +5.3% | +9.8% | 1.14% |
| XBI | -4.0% | +29.2% | +85.3% | +26.3% | +4.5% | +9.5% | 0.36% |
Total returns including dividends, from adjusted daily closes as of 2026-08-07. 3Y/5Y/10Y are annualized. Yield is trailing-12-month distributions over the last close. Past performance does not predict future results.
Project the growth of $10,000 in IYH vs XBI →
Shared Holdings(23)
The top 10 shared positions account for 77% of the overlap, led by REGN, AMGN and VRTX.
 REGNRegeneron Pharmaceuticals, Inc. COM | 1.32% | 1.24% | 1.24% |
|---|---|---|---|
 AMGNAmgen Inc. COM | 3.41% | 1.16% | 1.16% |
 VRTXVertex Pharmaceuticals Incorporated COM | 1.99% | 1.07% | 1.07% |
 ABBVAbbVie Inc. COM | 6.86% | 1.05% | 1.05% |
 GILDGilead Sciences Inc. COM | 2.99% | 1.04% | 1.04% |
 ALNYAlnylam Pharmaceuticals Inc. COM | 0.72% | 0.72% | 0.72% |
 INSMInsmed Inc COM PAR $.01 | 0.52% | 1.39% | 0.52% |
 BIIBBiogen Inc COM | 0.51% | 1.03% | 0.51% |
 NTRANatera Inc. COM | 0.50% | 1.18% | 0.50% |
 RVMDRevolution Medicines Inc COM | 0.47% | 1.33% | 0.47% |
 UTHRUnited Therapeutics Corporation COM | 0.44% | 0.95% | 0.44% |
 MRNAModerna Inc COM | 0.30% | 1.13% | 0.30% |
 INCYIncyte Corporation. COM | 0.28% | 1.09% | 0.28% |
 NBIXNeurocrine Biosciences Inc COM | 0.23% | 0.96% | 0.23% |
 ROIVRoivant Sciences Ltd SHS | 0.22% | 1.19% | 0.22% |
 IONSIonis Pharmaceuticals, Inc. COM | 0.22% | 0.72% | 0.22% |
 EXELExelixis, Inc. COM | 0.21% | 0.96% | 0.21% |
 BMRNBiomarin Pharmaceutical Inc. COM | 0.19% | 1.06% | 0.19% |
 HALOHalozyme Therapeutics Inc COM | 0.14% | 1.18% | 0.14% |
 VKTXViking Therapeutics Inc. COM | 0.06% | 1.16% | 0.06% |
 SMMTSummit Therapeutics Inc. COM | 0.05% | 0.98% | 0.05% |
 RAREUltragenyx Pharmaceuticals Inc COM | 0.04% | 0.92% | 0.04% |
 SRPTSarepta Therapeutics Inc COM | 0.04% | 0.73% | 0.04% |
Frequently Asked Questions
How much do IYH and XBI overlap?
IYH and XBI overlap by 10.7% of portfolio weight. They share 23 holdings (IYH holds 103 positions and XBI holds 149), based on each fund's latest SEC-reported holdings.
Is it redundant to own both IYH and XBI?
The two portfolios are 10.7% identical by weight. Owning both is not redundant. Most of each portfolio is distinct, so the funds can serve different roles.
What are the biggest shared holdings of IYH and XBI?
The largest positions held by both funds are REGN, AMGN, VRTX, ABBV and GILD. Together the top 10 shared positions account for 77% of the total overlap.
What does IYH own that XBI doesn't?
80 positions (78.1% of IYH) are unique to IYH, led by LLY, JNJ and UNH. In the other direction, 126 positions (75.8% of XBI) are unique to XBI.